Address: 38 Tongyan Road, Nankai University, Tianjin, China, 300350
Copyright © 2020 The Su Research Group 津ICP备20006080号
Introduction
Welcome to visit our group! We are a dynamic team of passionate chemists committed to developing novel strategies, methodologies, and reactions that address key challenges in organic synthesis and accelerate the discovery of new drugs. Our research focuses on the following areas:1) Tackling long-standing challenges in organic synthesis by creating novel strategies, synthetic methods, and chemi...
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11.12
2024
Our recent paper about enantioselective hydrophosphorylation of alkynes was selected as "Hot Paper" by Angew. Chem. editors and was one of "Most Accessed Papers" in October, 2024.Our recent work on the enantioselective hydrophosphorylation of alkynes has been recognized as a "Hot Paper" by the editors of Angewandte Chemie and ranked among the "Most Accessed Papers" in October 2024. -
11.05
2024
Our recent work on "Enantioselective 1,4-Borylamination via Copper-Catalyzed Cascade Hydroborylation and Hydroamination of Arylidenecyclopropanes" is offically accepted by J. Am. Chem. Soc, Congrats Yushen, Yalin, and Yingying!Compounds bearing both boryl and amino groups at distal positions are invaluable synthons for synthesizing pharmaceuticals, drug candidates, and natural products, but their catalytic enantioselective synthesis remains rarely explored. We developed an enantioselective 1,4-borylamination reaction through a copper-catalyzed cascade hydroborylation and hydroamination of arylidenecyclopropanes. This... -
10.06
2024
Our work on "Copper-Catalyzed Enantioselective Hydrophosphorylation of Unactivated Alkynes" is offically accepted by Angew. Chem. Int. Ed., Congrats Jie, Kang, Si-Mu, and Wen-Jun!The enantioselective addition of H-P(O)R1R2 to alkynes (hydrophosphorylation) offers a direct and efficient pathway to P-chiral compounds; however, the enantioselective hydrophosphorylation of unactivated alkynes remains a significant challenge, typically relying on noble palladium catalysts and proceeding via a kinetic resolution mechanism with less than 50% conversion. To address these limita... -
09.25
2024
Our review paper "Enantioselective borylative functionalization of internal alkenes: a platform for constructing vicinal stereocenters" is offically accepted by Chin. J. Chem., Congrats Yushen, Haotian, and Jiaxin!Vicinal stereogenic centers are ubiquitous structural scaffolds in both natural products and synthetic compounds, yet their enantioselective construction remains a significant challenge in organic synthesis. Transition-metal-catalyzed asymmetric borylative functionalizations of internal alkenes offer a promising strategy for the enantioselective installation of two adjacent chiral centers acros... -
08.28
2024
Website of the Su lab at Nankai University is online now!!Our website is online now! You are welcome to visit us!